Born in Quebec, Bruce graduated from high school in Vancouver, but spent his grade 12 year in Switzerland. Most often recognized as "the bad husband" in Double Jeopardy, Bruce also starred as John F. Kennedy in the film Thirteen Days, with Kevin Costner. He has appeared in numerous pictures, among them Ararat, Below, Exotica, The Sweet Hereafter, The Core, Rules of Engagement, Father's Day, Passenger 57, with Wesley Snipes, Hollywood Homicide, with Harrison Ford and I Robot, starring Will Smith. Recently released are the pictures Being Julia with Annette Bening and Racing Stripes. He won a 1995 Gemini award in Canada for his television performance in Road to Avonlea, received a Gemini nomination for The Little Kidnappers and a Genie nomination for his work in Atom Egoyan's Exotica. Bruce's breakthrough role was as a regular star on the popular St. Elsewhere series, playing Dr. Seth Griffin during the 1986-88 seasons. He has appeared in dozens of Movies of the Week and numerous television series and can be heard on many books on tape. Although most noted for his acting, Bruce is also a prolific singer/songwriter.
Bruce Greenwood was drawn to play the character of Tom in The Reuplic of Love because: "Tom's an innocent, optimistic guy. He's been around the block and yet he's naïve in terms of love, as he believes in the fable of love. I usually get to play guys with something up their sleeves but here's a guy who wears his heart on his! I play so many bad guys and I don't want to do that all the time, plus it was a chance to do something in Canada, which was attractive… A reason I also wanted to do this was that it's a fable, a very beautiful fable". On playing a good guy, Bruce Greenwood says: "It's trickier (playing good guys) in some ways. The decisions Tom makes are impulsive, and he has no agenda, so you have to be relaxed in a different way to when you are playing someone with one."
Currently starring in HBO's John from Cincinnati.